Are you in your 30s and still trying to conceive?

The term “biological clock”, which describes the declining ability of women to conceive with age, is used. Some women don’t care about the biological clock, either because they already have children or have made a personal decision to not have any. However, those who want to have children will become increasingly anxious as time goes on.

Many studies have shown that female fertility declines with age. In a 2014 committee opinion, which reflected the research and data collected by the American Congress of Obstetricians and Gynecologists (ACOG), the researchers found that during 12 insemination sessions, 73 percent of women under the age of 30 were able to get pregnant. A further 62 percent had the same success as women aged 31-35, while only 54 percent of those over 35 were able to get pregnant. The rate of miscarriage among women in their 30s has consistently increased.

Women over 35 who are trying to conceive will receive a more aggressive treatment. This is not a new discovery but no reason has been provided for this.

In older studies, the “cohesion” theory was posited as a possible explanation for women’s declining fertility rates. The theory was based on the assumption that older eggs suffer from a lack of cohesion. This is where the “glue”, which holds the chromosomes in place, stops working. In a study on mice, researchers found that the fertility rate of these mice was affected by other factors.

According to research at the University of Montreal Hospital, older mice eggs may also be instabil at the level of microtubules. The abnormal division of the cells is caused by this. How accurate are these mouse studies when it comes human fertility?

Dr. Dr. Copperman, director of RMA’s Division of Reproductive Endocrinology and Infertility, said that the mouse is the most common mammalian genetic model. The ovaries of mouse have many genetic and physiological similarities with humans despite the differences in ovarian ageing.


Scientists have made some amazing discoveries over the last decade in the field of research that could help to understand infertility and help couples and individuals become parents. There is still much to be done in the areas of infertility treatment, diagnosis and embryo selection.

The success rate for egg retrieval is currently 48.2 percent. This percentage drops as women age. The retrieval rate is only 3.2 percent at the age 42. However, women over 40 are six times more likely to pursue other methods of conception such as In Vitro Fertilization (IVF) than women under 35.

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